Top Substack Posts
Prior elevation of interleukin 10 (IL-10) seems to be a risk factor for developing persistent fatigue type symptoms.
My approach is not just to target symptoms of long COVID, but to identify and address the primary pathophysiology, such as chronic inflammation and immune dysregulation. By understanding these root causes, we can effectively mitigate predispositions and reduce the impact of long COVID in the future.
Elevated levels of the peptide hormone hepcidin seems to be central to the low iron pattern with long covid.
This pattern is likely to affect women more significantly than men.
The fact that a certain proportion of the population can have long Covid symptoms without having COVID-19 infection is significant.
It suggests the mechanism of this disease is related to immune processing of spike protein leading to ongoing immune activation.
The research continues to find the central pathophysiology to explain this observation.
Really important research which highlights significant longer term injury for patients with long Covid.
This study has demonstrated a 41% reduction of capillary permeability for long Covid patients. Elevated vascular endothelial growth factor (VEGF) now makes sense in long Covid. Highlighting the possible connection between VEGF and autoantibodies to G protein receptors.
This podcast was recorded on Friday the 26th of August 2022.
It came out of a tweet where Dave highlighted a few questions that needed to be answered.
What they don’t know about long Covid
- It’s pathophysiology
- How to treat it...
There are a few observed risks with long Covid that should not be underestimated.
It is noted significantly higher episodes of pulmonary embolus (clots in the lung) and myocardial infarctions (heart attacks).
Why would this occur?
